![]() ![]() Identifying sub-populations for whom TCD screening frequency could be safely reduced could lessen time burden on patients and caregivers and could be cost saving. Although TCD screening is non-invasive and safe, it consumes time and requires specialized equipment and trained examiners. Role of transcranial Doppler monitoring in the diagnosis of cerebral vasospasm after subarachnoid hemorrhage. The cumulative incidence of conversion from normal to conditional TCD velocities is dependent on age, whereby the risk is four times lower in children >10 years, compared to those <10 years of age 3. In close cooperation with scholars and research institutes throughout the world, DWL has been perfecting diagnostic methods, developing new applications, and creating Doppler systems. The estimated prevalence of normal TCD velocities is 83% 2 and these children will have received 15 TCD exams from ages 2 to 16 if all results remain within normal range. Transcranial Doppler Sonography (TCD) has its unique performance in measuring and analyzing flow velocity in blood vessels and detecting cerebral micro emboli. Screening intervals were developed following evidence from the STOP studies 1 (Figure 1). Current guidelines recommend annual TCD screening for children with SCA ages 2-16 years. ![]() Initiation of chronic blood transfusion for patients with confirmed abnormal TCD velocities (time-averaged mean velocity, TAMV≥200 cm/sec) is shown to effectively reduce primary stroke. ![]() Background Transcranial Doppler (TCD) screening of the large intracranial arteries can detect elevated blood velocity and is a strong predictor of stroke risk in children with sickle cell anemia (SCA, HbSS and HbSβ 0-thalassemia). ![]()
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